Other Areas of HPV ResearchHPV researchers are studying how the virus causes precancerous changes in normal cells and how these changes can be prevented. For example, scientists are developing HPV vaccines that will be stable at room temperature. The goal is to develop a vaccine that does not require refrigeration for storage and distribution, which could allow for its use in many climates and locations.
Laboratory research has indicated that HPVs produce proteins known as E5, E6, and E7. These proteins interfere with the cell functions that normally prevent excessive growth. For example, HPV E6 interferes with the human protein p53. This protein is present in all people and acts to keep tumors from growing. This research is being used to develop ways to interrupt the process by which HPV infection can lead to the growth of abnormal cells.
Researchers are also studying what people know and understand about HPV and cervical cancer, the best way to communicate to the public about the latest research results, and how healthcare providers are talking with their patients about HPV. This research will help ensure that the public receives accurate information about HPV that is easily understood, and will facilitate access to appropriate tests for those who need them.